Prof. Dr. Nasim Karim
Category: September 15, 2015

Dr Nasim Karim

Department Pharmacology (BUMDC)
Designation Principal BUHS-PGI &  HOD Pharmacology
Name Prof. Dr. Nasim Karim
Email Address
Phone Office Ext 021-35319491-9 (1072)
Research Area Pharmacology
Number of Publications 80
Degree Passing Year Majors University
MBBS 1989 Medicine, Surgery, Obst& Gynae, Eye, ENT, Pediatrics Dow Medical College, Karachi University
MPhil 2000 Pharmacology BMSI, JPMC, Karachi University
PhD 2005 Pharmacology University of Karachi, Pakistan
 Post- Doctoral Fellowship (HEC Awarded Scholarship) 2006-2007 Pharmacology Karachi UniversityUniversity of Medicine and Dentistry New Jersey (UMDNJ), USA
Teaching Experience
Designation From To Organization
Principal BUHS-PGI September 2022 To date Bahria University Medical & Dental college Karachi
Professor and HOD 29-9-2010 Till to Date Bahria University Medical & Dental College Karachi
Assistant Professor 19.08.2002 28-09-2010 Sindh Medical College – Dow University of Health Sciences (DUHS).Karachi
Lecturer/ Demonstrator 02.04.1995 18.08.2002 Dow Medical College, Karachi
1. Aamir K, Arif M, Dhanani MA, Karim N, Hussain A. The role of moxonidine in treatment of acute opioid abstinence syndrome. JAMC 2000; 12(4):9-12.
2. Karim N, Dhanani MA, Arif M. Effects of captopril-glibenclamide combination therapy on the metabolism in hypertensive NIDDM patients. Spectrum 2001 Feb;22(2):7-12.
3. Karim N, Aamir K, Dhanani MA. Effects of antihypertensive drug captopril on the metabolism in hypertensive NIDDM patients. Medical Channel 2001 Oct-Dec;7(4):45-47.
4. Arif M, Ahmed M, Karim N, Dhanani MA.The role of moxonidine in long term management of opioid dependence. J  Baqai Med Univ 2001 Jan-Jun, Jul-Dec;4(1&2):28-33.
5. Khalil Ahmed Shaikh, Tariq Sharafatullah, Ashfaq Ahmed qazi, Nasim Karim. Therapeutic efficacy of allopurinol (zyloric) in cutaneous leishmaniasis. Pakistan Journal of Pharmacology January 2003;20(1) 2003:43-7
6. Karim N, Ali SS, Dhanani MA, Ahmed K, Ahmed R.Effects of antihypertensive drug losartan on the metabolism in hypertensive NIDDM patients. Medical Channel 2003 Oct-Dec;9(4):45-48.
7. Ahmed K, Sharafatullah T, Kazi A, Karim N. Fixed drug eruption(FDE)most common adverse drug reaction.Pakistan Journal of Pharmacology 2004 Jan;21(1):1-5.
8. Ali SS, Karim N, Haider SS. Association of literacy of father with malnutrition among children under three years in rural areas of district Malir, Karachi. Medical Channel 2005 Jan-Mar;11(1):26-29.
9. Karim N, Ali SS, Hasan JA. Effect of losartan-glibenclamide combination therapy on the metabolism in hypertensive NIDDM patients. Pakistan Journal of Pharmacology 2005 Jan-Jun;22(1):17-22.
10. Hasan JA, Zaki M, Karim N. Rupture of gravid uterus-A three years study at Civil Hospital Karachi. JSP 2005 Jan-Mar; 10(1):20-22.
11. Ali SS, Karim N, Billoo GA, Haider SS. Association of literacy of mothers with malnutrition among children under three years in rural areas of district Malir, Karachi. JPMA 2005 Dec;55(12):550-3.
12. Karim N, Ali SS, Ahmed SP, Hasan JA. To observe the effects of metformin HCL on the carbohydrate metabolism in polycystic ovary syndrome. Pakistan Journal of Pharmacology. 2005 Jul-Dec;22(2):61-66.
13. Ansari MA, Ahmed SP, Kazi A, Karim N. Role of Alpha-2 agonist clonidine in attenuation of hot flashes in patients with acute opioid abstinence syndrome.Pakistan Journal of Pharmacology2005 Jul-Dec;22(2):47-51.
14. Kazi A, Ansari MA, Karim N, Dhanani MA. Gingival hyperplasia during verapamil therapy in hypertensive patients. Professional Med J 2006Jun;13(2):231-236.
15. Karim N, Ali SS, Ishaq M, Ansari MA, Ahmed SP. To compare the effects of metformin HCL with diet and exercise on the carbohydrate metabolism in polycystic ovary syndrome. Canadian Journal of Pure & Applied Sciences.2007Jul;1(1):57-61.
16. Nasim Karim. Effects of Type-1 Experimental Diabetes on Peripheral Sympatho-adrenal axis function. Post Doctoral Report 2007 UMDNJ-USA
17. Ishaq M, Ali SS, Karim N, Umrani NI, HasanN. Frequency of Hepatitis B and C virus among healthy volunteer donors at Taluka Hospital Sujjawal, district Thatta, Sindh. Ann. Abbasi Shaheed Hosp. Karachi & KMDC Coll.2007Dec;12(2):97-101.
18. Memon Z, Karim N, Ahmed SP, Ansari MA. Effect of metformin HCL versus Clomiphene Citrate on carbohydrate metabolism in polycystic ovarian syndrome. Pakistan Journal of Pharmacology.2008Jul;25(2):1-5.
19. Karim N, Berlin JR. Catecholamine Assay by Radioenzymatic Method-A Protocol. JDUHS 2008;2(3):121-126.
20. Karim N, Berlin JR. Indwelling jugular vein catheterization in the unrestrained conscious rats. Canadian Journal of Pure & Applied Sciences.2008;2(3):527-36.
21. Ishaq M, Ali SS, Karim N, Umrani NI, Hassan N. Treatment compliance and associated demographic factors in newly diagnosed tuberculosis patients on directly observed therapy-short course (DOTS). Ann Abbasi Shaheed Hosp. Karachi & KMDC Coll 2009;14(1):9-15.
22. Karim N, Ali SS. Jugular vein cannulation in rats-A review. Canadian Journal of Pure & Applied Sciences.2009;3(3):929-35.
23. Arif M, Sherwani B, Karim N, Turab MS, Jamali SN. Comparing the effect of verapamil and moxonidine in treatment of acute opioid abstinence syndrome. Medical Forum 2010;21(1):16-20.
24. Karim N.EKG in laboratory animals-Pre-requisites and Protocol. J basic Appl Sci 2010 Jan-Jun;6(1):69-72.
25. Arif M, Sherwani B, Turab MS, Jamali MS, Karim N. The role of verapamil in long term management of opioid dependence. Medical Forum.2010Feb;21(2):3-6.
26. Karim N, Hasan JA, Arif M, Ali SS, Turab MS. Effect of metformin on ovulation in PCOS. Medical Forum 2010Apr;21(4):19-24.
27. Karim N, Hasan JA, Ali SS. Heart rate variability-A review. J basic appl sci 2011Jan;7(1):71-77.
28. Memon Z, Karim N, Agha F. Effect of metformin versus clomiphene citrate on ovulation and conception rate in polycystic ovarian syndrome patients. J basic applsci 2011Jan;7(1):55-59.
29. Hasan JA, Karim N, Sheikh Z. Metformin prevents macrosomia & neonatal morbidity in gestational diabetes. Pak J Med Sci 2012April-June;28(3):384-389 [Impact Factor 0.01]
30. Karim N, Mustafa K, Hoor T. Effect of metformin versus diet & exercise on ovulation & menstrual regularity in PCOS. JBUMDC 2012 Jan-June;2(1):17-23
31. Nasim Karim, Sajid Abbas Jaffri ,Zubair Ahmed Tirmizi. Prescribing patterns in hospital Inpatients. JBUMDC 2012; 2(2):13-16
32. Mehtab Munir, Talea Hoor, Nasim Karim. OSPE in Pharmacology-Student`s Perspective. Commentary. JBUMDC 2012;2(2):32-34
33. Ali SS, Karim N, Munshi A B, Ahsan H. Persistent toxic impact of crude oil on mangroves as forge after Tasman spirit oil at Karachi coast of Pakistan. Canadian Journal on Computing in Mathematics, Natural Sciences, Engineering and Medicine. August,2013;4(4):291-298
34. Ahsan H, Karim N, Ali SS, Munshi A B, Shaukat S. Impact of pesticides contamination on nutritional values of marine fishery from Karachi coast of Arabian sea. Food and Nutritional Sciences. September 2013;4:924-932.doi:10.4236/fns.2013.49120
35. Ali SS, Karim N, Munshi A B, Siddiqui I Khan F A. Health Hazards among coastal villagers of Pakistan due to arsenic contaminated drinking water. Journal of Water Resource and protection. December 2013;5:1235-1241.
36. Rabia Arshad, Nasim Karim, Fahad Azam. Placental morphology and feto-maternal outcomes in gestational diabetes. JBUMDC 2013 Jan-June;1(1):30-33
37. Fuad Shaikh, Nasim Karim, Khalid Mahmood, Mohammad Ishaq Ghauri. Grip Strength Test: A simple Functional Adjunct Tool for Rheumatoid Arthritis. JBUMDC 2013;3(2):56-61
38. Rabia Arshad, Tahira Zamir, Nasim Karim. Placental Gross Morphology in Gestational Diabetes Mellitus. JBUMDC 2013;3(2):75-80
39. Tahira Zamir, Nasim Karim. Self Medication Practices in Pakistan. Commentary. JBUMDC2013;3(2);84-86
40. Alia Bano Munshi, Nasim Karim, Sohail Shaukat, Durdana Hashmi, Gregory Dale Boardman, George Joseph Flick. Toxicity of phthalate esters in fish and shellfish from Virginia beach using matrix solid phase dispersion (MSPD) and GC-MS. J.Chem. Soc. Pak 2013;35(6):1463-71 [Impact Factor: 0.621]
41. Rabia Arshad, Nasim Karim, Jahan Ara Hasan. Effects of insulin on placental, fetal and maternal outcomes in gestational diabetes mellitus. Pak J Med Sci 2014;30(2):240-4        [Impact Factor 0.098]
42. Talea Hoor, Riffat Farooqui, Jan Mohammad Shaikh, Nasim Karim. Salvadora Persica; anti-inflammatory activity in rats. Professional Med J 2014;21(1):70-4
43. Tahira Zamir, Nasim Karim, Farheen Navaid. Assessment of self medication practice among undergraduate medical students. Medical Channel 2014;20(2):9-13
44. Syed Sanwer Ali, Nasim Karim, Farooq Ahmed Khan, Alia Bano Munshi, Ishratullah Siddiqui, Shahla Basit.  A Direct Rapid Method to Estimate Blood Lead Level (BLL) among Coastal Villagers of Karachi J. Chem. Soc. Pak 2014;36(6):1181-8 [Impact Factor: 0.621]
45. Jahanara Ainuddin, Nasim Karim, Anjum Ara Hasan, Sanower Ali Naqvi. Metformin versus insulin treatment in gestational diabetes in pregnancy in a developing country. A randomized control trial. Diabetes Research and Clinical Practice 2015;107:290-9 [Published online 31st October 2014][Impact Factor: 2.536]
46. Jahanara Ainuddin, Nasim Karim, Sidra Zaheer, Syed Sanwer Ali, Anjum Ara Hasan Metformin treatment in type 2 diabetes in pregnancy: An active controlled, parallel-group, randomized, open label study in patients with type 2 diabetes in pregnancy. Journal of Diabetes Research. Volume 2015, Article ID325851,11 pages.


DOI: 2015[Impact Factor 3.536]

47. Rabia Arshad, Fuad Shaikh, Muhammad Omar Shamim, Nasim Karim, Fahad Azam. Placental Histology in Diet and Insulin Treated Gestational Diabetes. Medical Forum 2015;26(4):21-25
48. Shahla Basit, Nasim Karim, Alia Bano Munshi. Occupational lead toxicity in battery workers. Pakistan Journal of Medical Sciences. July – August 2015;31(4):775-780. doi:[Impact Factor 0.098]
49. Rabia Arshad, Nasim Karim, Muhammad Omar Shamim. Assessment of Risk Factors for Gestational Diabetes Mellitus. Pakistan Journal of Medicine and Dentistry. 2015;4(03):8-11
50. Fuad Sheikh, Rabia Arshad, Nasim Karim. Safety Profile of Methotrexate and Leflunomide in Rheumatoid Arthritis. JBUMDC. 2015;5(1) Jan-March : 20-24
51. Sadiq Mirza, Syed Sanowar Ali, Nasim Karim. Impact of Maternal Education on Children’s Health in Slum Area of Karachi. JBUMDC. 2015;5(1) Jan-March : 29-31
52. Rabia Arshad, Nasim Karim. Vasculo-Protective Cover: A Novel Action of Metformin. Review. JBUMDC 2015; 5(3): 105-108
53. Nasim Karim, Talea Hoor. Vitamin D – Not Just a Simple Vitamin. Commentary. JBUMDC 2015; 5(3): 143-145
54. Fuad Shaikh, Rabia Arshad, Fahad Azam, Nasim Karim. Methotrexate in Rheumatoid arthritis: Effect on blood, liver and renal laboratory parameters. JBUMDC. 2015;5(4):187-190
55. Syed Sanowar Ali, Nasim Karim. Lead and its health hazards. Review article. JBUMDC. 2016;6(2):69-75
56. Fuad Shaikh, Shaikh Nadeem Ahmed, Shamaila Khalid, Nasim Karim. Leflunomide in Rheumatoid arthritis: Effect on laboratory parameters. JBUMDC. 2016;6(2):101- 105
57. Nasim Karim. Cell Phone-Addiction may lead to misery. Editorial. JBUMDC.2016;6(3):134-135
58. Nasim Karim, Ayesha Khan, Afsheen Nazar. Heavy metal-Arsenic. Review Article. JBUMDC.2016;6(3):136-141
59. Talea Hoor, Riffat Farooqui, Nasim Karim, Afsheen Nazar. Errors in prescription writing: an audit of general practitioners. JBUMDC.2016;6(3):182-185
60. Riffat Farooqui, Tahira Zamir, Rafeeq Alam Khan ,Nasim Karim,. Effect of Herbal Syrup Linkus on Acute and Gross Toxicity and Electrolytes in Blood and Organs JBUMDC.2016;6(4): 223-227 Oct-Dec 2016 
61. Talea Hoor, Nasim Karim, Ayesha Khan. Errors in Prescription Writing of Consultants


JBUMDC.2016;6(4): 241-244 Oct-Dec 2016 

62. Rabia Arshad, Muhammad Adnan Kanpurwala,  Nasim Karim , Jahan Ara Ainuddin Effects of Diet and Metformin on Placental Morphology in Gestational Diabetes Mellitus. Pak J Med Sci .  November-December 2016: 32(6) : 1522-1527[Impact Factor 0.544]
63. Nasim Karim. Lead & Triple Cs-Children, Candies and Chocolates. Editorial. JBUMDC.2017;7(3):136-137
64. Tahira Zamir, Nasim Karim, Ishrat Younus, Zeeshan Feroz. Selfmedication patterns among undergraduate medical students: A cross sectional institution based study.PTB Reports-Pharmacology, Toxicology and Biomedical Reports International Journal.2017;3(2):43-46
65. Rabia Arshad,Samia Khannum Fuad Shaikh, Nasim Karim. Feto-maternal outcomes and Glycemic control in Metformin versus insulin treated Gestational Diabetics. Pak J of Med Sci (PJMS).2017;33(5):1182-1187[Impact Factor 0.544]
66. Riffat farooqui, Nasim Karim, Talea Hoor. Potential drug-drug interactions among patients in a medicine out-patient setting. Pak J Med Sci January-February 2018;34(1) : 144-148 [Impact Factor 0.544]
67. Nasim Karim. Copper and Human Health- A Review JBUMDC 2018; 8(2):117-122
68. Nasim Karim Impact of dietary measures in autoimmune diseases. Editorial. JBUMDC 2019; 9(1):1-2
69. Ayesha Khan, Nasim Karim, Jahanara Ainuddin. The triad of PCOS, infertility and metformin. Review article. JBUMDC 2019; 9(1):67-71
70. Rabia Arshad, Zahida Sheikh, Kausar Aamir, Nasim Karim, Tahira Asad. Pregnancy consequences in diet controlled mild gestational hyperglycemia. Pakistan Journal of Medicine and Dentistry (PJMD) 2019;8(03):40-45
71. Ayesha Khan, Nasim Karim, Jahanara Ainuddin, Faisal Faheem. Polycystic ovarian syndrome: Correlation between clinical hyperandrogenism, anthropometric, metabolic and endocrine parameters. Pak J Med Sci September-October 2019;35(5): 1227-1232 [Impact Factor 0.834]
72. Mamoora Arslaan, Nasim Karim, Wahab Baksh Kadri, Shama Asghar. Local Drug Delivery to Treat Chronic Periodontitis. JBUMDC 2020;10(2):158-162
72. Mamoora Arslaan, Nasim Karim, Wahab Baksh Kadri, Shama Asghar. Local Drug Delivery to Treat Chronic Periodontitis. JBUMDC 2020;10(2):158-162
73. Ayesha Khan, Nasim Karim, Jahan Ara Ainuddin. Impact of pioglitazone on anthropometric and metabolic parameters in PCOS infertile women. JIIMC 2021;16(2):101-105
74. Mamoora Mirza, Nasim Karim, Wahab Baksh Kadri, Shama Asghar. Clinical Efficacy of 1% Metformin gel and Systemic Doxycyline in Chronic Periodontitis: A Randomized Clinical Trial. J Liaquat Uni Med Health Sci. July – September 2021;20(03):204-8. doi: 10.22442/jlumhs.2021.00844
75. Nasim Karim.Commentary. Ameliorate Patient Care and Safety with Technology. JBUMDC  2021;11(4):187-189
76. Mamoora Arslaan, Nasim Karim, Mehr Fatima.  Clinical Efficacy of 1% Metformin and Alendronate intra-pocket gel in moderate localized chronic periodontitis. Rawal Medical Journal. Jan-March 2022; 47(1):112-115
77. Bibi Kulsoom, Nasim Karim. Sound: production, perception, hearing loss & treatment options: Narrative review.13-12-2021. JPMA April 2022;72(4):725-732. (IF=0.781)   DOI:
78. Ayesha Khan, Mehtab Munir, Hafiza Tuseef Sayyar, Hina Amjad, Nasim Karim. Effect of metformin on BMI, body circumferences and metabolic parameters in polycystic ovarian syndrome. Rawal Medical Journal Oct-Dec 2022; 47(4): 948-951.
79. Asra Khan Pahore, Shagufta Khan, Nasim Karim. Anticancer effect of Illicium verum (star anise fruit) against human breast cancer MCF-7 cell line. On-line November 2022.Pak J Med Sci. January – February 2023; 39(1):1-5 (IF= 1.088)
80. Ayesha Khan, Mamoora Arslaan,Asra Khan Pahore, Hafiza Tauseef Sayyar, Nasim Karim.
Outcomes of Pioglitazone and metformin on anthrpometric, metabolic and endocrine variables in polycystic ovary syndrome. PJMHS. Jan 2023;17(01):220-222